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Ecler Ercole Jaqua, MD, MBA
Mai-Linh N. Tran, MD
Marry Hanna, MD

American Family Physician. 2024;109(1):1

This clinical content conforms to AAFP criteria for CME.

Author disclosure: No relevant financial relationships.

Abstract

Alzheimer disease is a progressive, neurodegenerative disorder characterized by the accumulation of amyloid beta plaques and hyperphosphorylated tau proteins. Alzheimer disease affects cognitive function, leading to memory loss and impairment in activities of daily living. Approximately 6.9 million people in the United States 65 years and older live with Alzheimer disease, a number expected to double by 2060. Although there is no cure for Alzheimer disease, treatments are available to manage symptoms. Tools such as the Diagnostic and Statistical Manual of Mental Disorders, 5th ed., criteria aid in identifying major neurocognitive disorders. The evaluation involves a comprehensive medical history, cognitive examinations, and collateral information.


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Nonpharmacologic Management

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Author disclosure: No relevant financial relationships.

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